CJC-1295 / Ipamorelin
The Gold Standard GH Stack.
CJC-1295 and Ipamorelin work together to naturally stimulate your pituitary gland to produce more growth hormone — without the risks, cost, or legal complexity of synthetic HGH. Physician-prescribed, lab-monitored, and compounded by licensed pharmacies.
What is CJC-1295/Ipamorelin?
CJC-1295/Ipamorelin is a combination of two complementary growth hormone secretagogues — peptides that signal your pituitary gland to produce and release more of your own growth hormone. CJC-1295 is a GHRH (growth hormone releasing hormone) analog that extends the GH release window, while Ipamorelin is a selective GH secretagogue that amplifies the GH pulse. Together they are the most widely prescribed GH peptide combination in physician-supervised anti-aging medicine.
CJC-1295 (with DAC)
A growth hormone releasing hormone analog with a Drug Affinity Complex (DAC) modification that extends its half-life to approximately six to eight days. This means your body maintains consistently elevated GH levels rather than short-lived spikes. CJC-1295 works with your body's natural feedback loops — it does not suppress your pituitary gland.
Ipamorelin
A selective growth hormone secretagogue that triggers a strong, clean pulse of GH release. Unlike older peptides like GHRP-6, Ipamorelin does not significantly increase cortisol or prolactin, making it one of the safest and best-tolerated GH peptides available. When combined with CJC-1295, it amplifies the peak of each GH pulse for a synergistic effect.
At Revive Low T Clinic in Kennewick, WA, CJC-1295/Ipamorelin is prescribed by licensed naturopathic physicians following a full evaluation including IGF-1 levels (the primary biomarker for growth hormone status), metabolic markers, and a comprehensive physical exam. Protocols are compounded by Empower Pharmacy or Hallandale Compounding Pharmacy and shipped to your home.
How does CJC-1295 with Ipamorelin work?
CJC-1295 and Ipamorelin work through distinct but complementary mechanisms. CJC-1295 binds to GHRH receptors in the pituitary gland and extends the duration of each natural GH release pulse. Ipamorelin binds to ghrelin receptors and independently triggers a strong, additional GH pulse. Together, they produce a sustained, synergistic elevation in growth hormone and IGF-1 levels that mimics the hormonal profile of a significantly younger man.
Growth hormone declines approximately 14% per decade after age 30. By the time a man reaches 50, his GH output is often less than half of what it was at 25. This decline is associated with increased abdominal fat, loss of lean muscle, declining sleep quality, slower wound healing, reduced skin elasticity, and lower energy. CJC-1295/Ipamorelin addresses this decline by restoring more youthful GH pulsatility without introducing exogenous (external) growth hormone.
Protocols are typically administered before bedtime as a subcutaneous injection, timed to align with the body's natural GH release cycle during deep sleep. This approach amplifies the largest natural GH pulse of the day — the one that occurs during slow-wave sleep — rather than working against the body's existing rhythms. Most patients report dramatically improved sleep quality within the first week of starting the protocol.
What are the anti-aging benefits of CJC-1295?
The anti-aging benefits of CJC-1295/Ipamorelin include significant improvements in body composition (fat loss and lean muscle gain), deeper and more restorative sleep, enhanced cognitive function and mental clarity, improved skin elasticity, faster recovery from exercise and injury, and increased energy and vitality. These benefits develop progressively over an 8 to 12 week cycle.
Fat Loss
GH directly stimulates lipolysis — the breakdown of stored body fat. Measurable reductions in abdominal fat often appear within 6 to 8 weeks of starting the protocol.
Lean Muscle
GH promotes protein synthesis and muscle recovery. Combined with resistance training, patients typically gain lean mass while losing fat — a simultaneous body recomposition effect.
Deeper Sleep
GH is primarily released during deep sleep. CJC-1295/Ipamorelin amplifies this natural cycle. Patients consistently report the best sleep of their lives within the first week of starting the protocol.
Cognitive Function
Growth hormone supports brain health and cognitive performance. Many patients report improved mental clarity, focus, and mood stability alongside the physical changes.
Important context: Growth hormone declines approximately 14% per decade after age 30. CJC-1295/Ipamorelin does not add external GH — it restores the pituitary's own output to more youthful levels. This is meaningfully different from synthetic HGH, which suppresses the body's own production and carries a significantly higher risk and cost profile.
How much does CJC-1295/Ipamorelin cost?
CJC-1295/Ipamorelin at Revive Low T Clinic costs $200–350 per cycle, depending on dosage and cycle length. The initial consultation is $99 and includes a physician exam, 51-analyte lab panel with IGF-1, and protocol recommendation. Compounding, shipping, reconstitution supplies, and injection materials are included in the cycle price.
Initial Consultation
Physician exam, 51-analyte labs with IGF-1, and protocol recommendation. Covers TRT evaluation simultaneously if applicable.
CJC-1295 + Ipamorelin Cycle
8–12 week cycle. Combined formulation compounded by Empower or Hallandale. Includes supplies and injection materials.
vs. Synthetic HGH
Synthetic HGH costs $800–2,000/month. CJC-1295/Ipamorelin achieves comparable GH optimization at a fraction of the cost — and without HGH's legal complexity.
Insurance coverage: CJC-1295/Ipamorelin is a compounded peptide and is not covered by health insurance. HSA and FSA funds may be used for physician-supervised peptide therapy. Your Revive physician can provide documentation to support HSA/FSA reimbursement where applicable.
Can CJC-1295 be combined with TRT?
Yes — CJC-1295/Ipamorelin is one of the most effective add-ons to testosterone replacement therapy. Testosterone and growth hormone operate through complementary pathways: testosterone drives muscle protein synthesis, libido, mood, and energy; growth hormone drives fat metabolism, tissue repair, sleep quality, and cellular regeneration. Optimizing both simultaneously produces results significantly greater than either therapy alone.
Many patients at Revive start with TRT and add a CJC-1295/Ipamorelin cycle once their testosterone levels are stabilized — typically 60 to 90 days after starting TRT. The combined effect on body composition is particularly significant: patients consistently report losing abdominal fat while gaining lean muscle simultaneously, a result that is difficult to achieve with either therapy alone.
The synergy extends beyond body composition. Recovery from workouts accelerates substantially. Sleep deepens further. Mental clarity sharpens. For men over 40 who are experiencing the compounded effects of declining testosterone and declining growth hormone simultaneously, addressing both pathways is the most comprehensive approach to age-related hormonal decline available in clinical medicine today.
TRT Alone
- ✓ Restores testosterone levels
- ✓ Improves energy, libido, mood
- ✓ Supports muscle growth
- ○ Limited effect on growth hormone
- ○ Moderate fat loss
TRT + CJC-1295/Ipamorelin
- ✓ Restores testosterone AND growth hormone
- ✓ Amplified energy, libido, sleep, mood
- ✓ Enhanced muscle growth + faster recovery
- ✓ Significant fat loss (especially visceral)
- ✓ Anti-aging: skin, cognition, vitality
What are the side effects of CJC-1295/Ipamorelin?
CJC-1295/Ipamorelin has a favorable safety profile. The most common side effects are mild and temporary: water retention in the first one to two weeks, tingling or numbness in the hands or feet (a sign of elevated GH), increased appetite, and vivid dreams. Ipamorelin specifically does not significantly increase cortisol or prolactin, which distinguishes it from older GH peptides and contributes to its favorable tolerability.
Common Side Effects
- Water retention — Mild fluid retention in the first 1–2 weeks. Resolves as the body adjusts to elevated GH levels.
- Tingling or numbness — A sign of elevated GH. Usually mild and temporary. If persistent, your physician adjusts the dose.
- Increased hunger — GH stimulation temporarily increases appetite. Manageable with dietary awareness. Most patients view this positively when lean-gaining.
- Vivid dreams — Very common. A direct result of deeper sleep cycles. Most patients consider this one of the best effects of the protocol.
Safety Monitoring at Revive
- IGF-1 baseline — Measured before starting to confirm GH deficiency and establish a monitoring target.
- Mid-cycle check-in — IGF-1 and metabolic markers rechecked at the midpoint. Dose adjusted as needed.
- End-of-cycle labs — Full panel to evaluate response, safety, and whether to continue or modify.
- Blood glucose monitoring — GH can affect insulin sensitivity. Fasting glucose and HbA1c are monitored throughout.
Physician supervision is what makes this safe. The biggest risk with growth hormone peptides is using unregulated products from online sources without proper lab monitoring. At Revive, every protocol is pharmaceutical-grade, every patient has IGF-1 monitored throughout their cycle, and dose adjustments are made proactively — not reactively.
CJC-1295/Ipamorelin Protocol at Revive
Administration
Subcutaneous injection, typically administered before bed to align with the body's natural GH release cycle during deep sleep. Injection training is provided in-person at the clinic before you self-administer at home.
Typical Cycle Length
8 to 12 weeks on, followed by a 4-week break to maintain receptor sensitivity. Cycles can be repeated based on goals and lab results. Many patients do 2 to 3 cycles per year on a maintenance basis.
Dosing
CJC-1295: 1 to 2 mg per week. Ipamorelin: 200 to 300 mcg per injection, typically 5 nights per week. Your physician personalizes the dosing schedule based on your IGF-1 levels, body composition goals, and response.
Pharmacy
Compounded and shipped by Empower Pharmacy (Houston, TX) or Hallandale Compounding Pharmacy (Hallandale Beach, FL). Both are FDA-inspected facilities. Medications arrive within 3–5 business days in temperature-controlled packaging with reconstitution supplies included.
Explore Your Full Treatment Options
All Peptide Therapy
BPC-157, CJC-1295, and Ipamorelin. Overview of all peptide options, protocols, and pricing at Revive.
View Peptide Therapy →BPC-157
Tendon, ligament, muscle, and gut healing. The top recovery peptide — often paired with CJC-1295/Ipamorelin.
Learn About BPC-157 →Testosterone Therapy
TRT with in-person exams, 51-analyte labs, and pharmacy prescriptions. Pairs powerfully with CJC-1295/Ipamorelin.
Learn About TRT →Start Your GH Optimization Protocol
Schedule your $99 first visit — includes a physician consultation, in-person exam, and comprehensive 51-analyte lab panel with IGF-1. We will evaluate your growth hormone status and design a personalized CJC-1295/Ipamorelin protocol around your goals.
Schedule Your Consultation →Or call us: (509) 628-2727 · Kennewick, WA
Peptide Therapy Overview · BPC-157 Recovery Peptide · Testosterone Therapy